Influence of MC4R mutations in traits of tested Danube white purebred pigs

Katya Eneva1, Apostol Apostolov1, Radka Nedeva1, Atanas G. Atanasov4,5, Bogdan Szostak2 and Radostina Stoikova3
1 Agricultural Academy, Agricultural Institute, 9700 Shumen, Bulgaria
2 University of Life Science in Lublin, Faculty of Biology and Animal Breeding, 22-950 Lublin, Poland
3 Agricultural Academy, Institute of Animal Science, 2230 Kostinbrod, Bulgaria
4 Institute of Genetics and Animal Breeding, Polish Academy of Sciences,44-335 Jastrzebiec, Poland
5 University of Vienna, Department of Pharmacognosy,1010-1400 Vienna, Austria

Abstract

Eneva, K., Apostolov, A., Nedeva, R., Atanasov, A. G., Szostak, B. & Stoikova, R. (2021). Influence of mc4r mutations in traits of tested Danube white purebred pigs. Bulg. J. Agric. Sci., 27 (2), 374–378

Restriction analysis (restriction fragment length polymorphism, RFLP) for establishing of MC4R polymorphisms with 81 Danube white purebred pigs was carried out. Genotypes and alleles frequencies of MC4R gene were classified as follows: the number of heterozygous animals MC4RAB -72.8% was the highest one and significantly lower for both homozygous genotypes 12.3-14.8%. The allele frequencies – MC4RA and MC4RB were close as the difference from 5.04% was in advantage for favorable MC4RB alleles.
It was established that as a result of the mutation of Asp298Asn pigs with genotype MC4RBB exceeded animals of the other genotypes as the differences for the following traits: back fat at point Х2, meat content and back fat MLD were significant (Р ≤ 0.05).
The present study conducted with pigs from the Danube white breed gives us reason to assert that the MC4R gene can be used as a reliable genetic marker for the selection of fattening and carcass traits measured during the testing period of 90 kg live weight.

Keywords: MC4R gene mutation; Danube white pigs

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