Flavan-3-ols in Selected Bulgarian Red Wines

National Center of Hygiene, Medical Ecology and Nutrition, BG-1431 Sofia, Bulgaria


S. TSANOVA-SAVOVA, S., 2003. Flavan-3-ols in selected Bulgarian red wines. Bulg. J. Agric. Sci., 9: 487–491

The Flavan-3-ols are biologically active substances with a number of beneficial health effects. Red wines are one of their main dietary sources. The lack of data for flavan-3-ol in Bulgarian wines set the aim of our study to determine (+)-catechin and (–)-epicatechin concentrations in 5 red vine varieties, produced in Bulgaria (Gamza, Mavrud, Melnik, Merlot and Cabernet Sauvignon). An RP-HPLC method with fluorescence detection was developed using an isocratic elution system of 9 % acetonitirile in 2 % acetic acid. Among the analyzed wines the (+)-catechin concentrations vary form 74.5 mg/l (Merlot) to 123.0 mg/l (Melnik), and (–)-epicatechin concentrations range from 13.3 (Gamza) to 35.2 mg/l (Mavrud). The typical Bulgarian red wines Mavrud and Melnik are characterized with higher flavan-3-ols concentrations (130.7–154.8 mg/l), followed by Gamza, Cabernet-Sauvignon, and Merlot wines (89.4–100.4 mg/l). The present data are important for characterization of wines' biologically active substances, and could be used for formulation of nutritional climes as well.

Key words: red wine, Bulgaria, flavan-3-ols, health, dietary sources, Gamza, Mavrud, Melnik, Merlot, Cabernet Sauvignon, biologically active substances, nutritional climes