Comparative Study of Gammaglobulin Preparations for Gastroenteritis Prophylaxis in Newborn Calves

Yu. ENCHEVA, A. BOYADZHIEVA, N. KORUDZHIISKI and E. CHALEVA
National Diagnostic and Research Veterinary Institutes, BG-1606 Sofia, Bulgaria

Abstract

ENCHEVA, Yu., A. BOYADZHIEVA, N. KORUDZHIISKI and E. CHALEVA, 2005. Comparative study of gammaglobulin preparations for gastroenteritis prophylaxis in newborn calves. Bulg. J. Agric. Sci., 11:357-362

Comparative studies of gammaglobulin preparations for gastroenteritis prophylaxis in newborn calves were performed. The trial comprised 53 newborn calves. Animals were divided into 5 groups as follows: Group I - 10 calves, injected intramuscularly immediately after calving with 20 ml normal bovine gammaglobulin; Group II - 10 calves, treated per os before the first colostrum intake with 50 ml bovine gammaglobulin; Group III - 13 calves, injected intramuscularly immediately after birth with 20 ml gammafer; Group IV - 10 calves, treated per os immediately after birth with 30 ml gentaglobin-bovis; Group V - 10 calves, control animals - untreated.
The calves were monitored for 14 days for gastroenteritis incidence, severity, disease duration and mortality.
It was found that per os application of gentaglobin-bovis and gammaglobulin had the best preventive effect, reducing gastroenteritis incidence in calves 3.3 (t>0.001) and 1.4 times (t>0.05), compared to intramuscular application.

Key words: newborn calves, gammaglobulin, gammafer, gentaglobin-bovis, gastroenteritis, prophylaxis
Abbreviations: MIC - minimal inhibitory concentration